What is Cholesterol?Cholesterol is a sterol (a combination steroid and alcohol). Cholesterol is a lipid found in the cell membranes of all tissues, and it is transported in the blood plasma of all animals. Because cholesterol is synthesized by all eukaryotes, trace amounts of cholesterol are also found in membranes of plants and fungi.The name originates from the Greek chole- (bile) and stereos (solid), and the chemical suffix -ol for an alcohol, as researchers first identified cholesterol in solid form in gallstones by Francois Poulletier de la Salle in 1769. However, it is only in 1815 that chemist Eugene Chevreul named the compound "cholesterine".[2]Most of the cholesterol is synthesized by the body and some has dietary origin. Cholesterol is more abundant in tissues which either synthesize more or have more abundant densely-packed membranes, for example, the liver, spinal cord and brain. It plays a central role in many biochemical processes, such as the composition of cell membranes and the synthesis of steroid hormones. Cholesterol is insoluble in blood, but is transported in the circulatory system bound to one of the varieties of lipoprotein, spherical particles which have an exterior composed mainly of water-soluble proteins. The main types, low-density lipoprotein (LDL) and high-density lipoprotein (HDL) carry cholesterol from and to the liver.According to the lipid hypothesis, abnormally high cholesterol levels (hypercholesterolemia) and abnormal proportions of LDL and HDL are associated with cardiovascular disease by promoting atheroma development in arteries (atherosclerosis). This disease process leads to myocardial infarction (heart attack), stroke and peripheral vascular disease. As high LDL contributes to this process, it is termed "bad cholesterol", while high levels of HDL ("good cholesterol") offer a degree of protection. The balance can be redressed with exercise, a healthy diet, and sometimes medication. |
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British Journal of Pharmacology - Central control of blood However, the response times at which different cardiovascular mechanisms operate differ considerably (e.g. blood pressure control by the RAS is slower than IngentaConnect IDENTIFICATION OF BLOOD PRESSURE CONTROL MECHANISMS Most of the secondary mechanisms associated with hypertension are generally . The aim of treatment should be blood pressure control to <140/90 mmHg for Hypertension - Wikipedia, the free encyclopedia Scientists from King's College London describe a new molecular mechanism for blood pressure control, an oxidant-induced vasorelaxation: Scientists Report New Blood Pressure Control Mechanism - Medgadget NEUROHUMORAL CONTROL OF CIRCULATION AND HYPERTENSION. Effect of a perinatal high-salt diet on blood pressure control mechanisms in young Sprague-Dawley rats Effect of a perinatal high-salt diet on blood pressure control Elucidation of central blood pressure control mechanism using gene manupulation : Preparation of a cerebral hypertension model accelerated in Central nervous system mechanisms in blood pressure control Brainstem control mechanisms in blood pressure regulation. Department of Physiology and Pharmacology Julian.F.R.Paton@bristol.ac.uk University of Bristol - Bristol Neuroscience Blood Pressure and Hormonal Control Mechanisms summary with 3 pages of encyclopedia entries, research information, and more. Blood Pressure and Hormonal Control Mechanisms | World of Anatomy and long-term control of the blood pressure. Several pressure control mechanisms react within. seconds. Thefirst defense to low arterial pressure Mechanisms of Heart Rate and Arterial Blood Pressure Control Central control of blood pressure by nitrergic mechanisms in organum vasculosum laminae terminalis of rat brain. M -T Lin1, S -P Pan2, J -H Lin3 and Y -L Blood pressure variability and cardiovascular control mechanisms To aid our understanding of the mechanisms in-. volved in the control of blood pressure, a number of. animal models of hypertension have been develop- |
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