What is Cholesterol?

Cholesterol is a sterol (a combination steroid and alcohol). Cholesterol is a lipid found in the cell membranes of all tissues, and it is transported in the blood plasma of all animals. Because cholesterol is synthesized by all eukaryotes, trace amounts of cholesterol are also found in membranes of plants and fungi.The name originates from the Greek chole- (bile) and stereos (solid), and the chemical suffix -ol for an alcohol, as researchers first identified cholesterol in solid form in gallstones by Francois Poulletier de la Salle in 1769. However, it is only in 1815 that chemist Eugene Chevreul named the compound "cholesterine".[2]Most of the cholesterol is synthesized by the body and some has dietary origin. Cholesterol is more abundant in tissues which either synthesize more or have more abundant densely-packed membranes, for example, the liver, spinal cord and brain. It plays a central role in many biochemical processes, such as the composition of cell membranes and the synthesis of steroid hormones. Cholesterol is insoluble in blood, but is transported in the circulatory system bound to one of the varieties of lipoprotein, spherical particles which have an exterior composed mainly of water-soluble proteins. The main types, low-density lipoprotein (LDL) and high-density lipoprotein (HDL) carry cholesterol from and to the liver.According to the lipid hypothesis, abnormally high cholesterol levels (hypercholesterolemia) and abnormal proportions of LDL and HDL are associated with cardiovascular disease by promoting atheroma development in arteries (atherosclerosis). This disease process leads to myocardial infarction (heart attack), stroke and peripheral vascular disease. As high LDL contributes to this process, it is termed "bad cholesterol", while high levels of HDL ("good cholesterol") offer a degree of protection. The balance can be redressed with exercise, a healthy diet, and sometimes medication.

blood pressure variability
ScienceDirect - The Lancet : Blood pressure variability in elderly
Sirâ”Tudor Vagaonescu and colleagues report on cardiovascular damage sustained because of blood pressure variability in elderly patients with hypertension

Impact of acute blood pressure variability on ischemic stroke
Impact of acute blood pressure variability on ischemic stroke outcome. L. G. Stead, MD, R. M. Gilmore, MRCPI, K. C. Vedula, BS, A. L. Weaver, MS,

Blood pressure variability as an adverse prognostic risk factor in
We prospectively studied the association between systolic blood pressure variability and cardiovascular mortality and mortality from all causes in end-stage

Analysis of heart rate and blood pressure variability during nasal
heart rate variability (HRV and the systolic blood. pressure variability (SBP and systolic blood pressure variability (SBPV) are

American Journal of Hypertension - Blood Pressure Variability: The
The American Journal of Hypertension, a peer reviewed journal, provides a forum for scientific inquiry of the highest standard in the fields of hypertension

Relationship between Leuko-Araiosis and Blood Pressure Variability
Relationship between Leuko-Araiosis and Blood Pressure Variability in the Elderly François Puisieuxa, Pascal Monacaa, Dominique Deplanqueb,

IngentaConnect Blood Pressure Variability And Organ Damage
Blood pressure variability (BPV) is expressed as the standard deviation of the average blood pressure (BP). Blood pressure variability is increased in

Blood pressure variability and baroreflex sensitivity are not
as the blood pressure variability (BPV). This new parameter. of cardiovascular function can be Measurement of blood pressure and its variability Rats

ABC of hypertension: Blood pressure measurement -- Beevers et al
The inherent variability of blood pressure; The defence reaction .. The elderly are subject to considerable blood pressure variability, which can lead to

heart rate and blood pressure variability
Loss of heart rate variability, increased blood pressure variability , and impaired baroreflex appear to be characteristic of moderate to severe POTS and

New Way to Express Ambulatory Blood Pressure Variability
Ambulatory blood pressure variability, measured as the standard deviation of the overall 24-hour blood pressure recording, has been shown to have a

Factors influencing blood pressure and heart rate variability in
The correlation (r) between baroreceptor reflex sensitivity and blood pressure variability was -0.47 (p less than 0.0002). Baroreceptor reflex sensitivity

eMJA: Ambulatory blood pressure monitoring
The first device for non-invasive ambulatory blood pressure monitoring was . blood pressure load, dayâ“night difference, blood pressure variability) is

Blood pressure variability: Lessons learned from a systematic review.
6) Knowledge of the expected variability of blood pressure measurements can be used to detect data, which is of questionable validity.

New Definitions and New Classes of Antihypertensive Drugs Show Promise
Blood Pressure Variability Not an Independent Predictor of Outcome in When looking only at daytime blood pressure variability, event rates per 100

Estimation of arterial blood pressure variability by spectral
Keywords: blood pressure variability, spectral analysis, Finapres. Print publication: Issue 3 (August 1996) Received 15 January 1996, in final form 17 May

The mechanism of blood pressure variability: Study in patients
Background: Several studies have shown that heart rate variability plays an anti-oscillatory role in the regulation of blood pressure variability in humans.

The Effect Of Blood Pressure Variability On Cognitive Function In
The Effect Of Blood Pressure Variability On Cognitive Function In Older Subjects from Age and Ageing in Health provided free by Find Articles.

Blood Pressure Variability Increases Risk For Stroke Death
Erratic blood pressure during the first hours after a stroke dramatically lowers the chances of survival. That's the finding of a Mayo Clinic study


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